Stanovení vývojového potenciálu lidských embryí pomocí omických disciplín
Klíčová slova:
asistovaná reprodukce, lidské embryo, mimotělní oplodnění, genomika, transkriptomika, proteomika, metabolomikaAbstrakt
This review defines limits of currently used techniques to assess developmental capacity of human embryos in assisted reproduction and provides an overview of techniques assessing embryo's physiology on levels of genomics, transcriptomics, proteomics and metabolomics. Basic principles of respective techniques are included. Discovered biomarkers are discussed with respect to biochemical functions and their prognostic values of embryonal development.